Work

17 01 Base Architecture Esophageal Adenocarcinoma

Year: 2026

Type: article

Abstract: Esophageal adenocarcinoma arises at the squamocolumnar junction (SCJ), a region of inherentectoderm-endoderm transition subjected to chronic gastric acid reflux . Unlike hepatocellular carcinoma where microenvironmental parameters exhibit modest variation , EAC developsunder extreme pH volatility: luminal pH oscillates 0.2 ↔ 0.7 (normalized scale) with circadianreflux cycles, creating persistent selection pressure for adaptive plasticity . I try to take a snaphot at the carconomas base architecture and overall dynamics in order to be able to better simulate various senarious in which different elements and vectors are permutated.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18167524

Author: Stefan, Ionut Alexandru

Language: English

Topic: Esophageal Cancer Research and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7119465373

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