Work

Structure-Based Design of Pan-Selective Peptide Epoxyketones for the Three Human Immunoproteasome Active Sites

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02639

Authors: Patrick M. Dekker, Eva M. Huber, Elmer Maurits, Xingzao Wang, Wolfgang Heinemeyer, Bogdan I. Florea, Michael Groll, Herman S. Overkleeft

Institutions: Leiden University, Technical University of Munich

Language: English

Topic: Ubiquitin and proteasome pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Deutsche Forschungsgemeinschaft, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Bayerische Akademie der Wissenschaften

Award: G7967513049

OpenAlex ID: W7119470795

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Cites: 37

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