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20 02 Metastasis Base Architecture Acute Myeloid Leukemia AML

Year: 2026

Type: article

Abstract: Extramedullary involvement in acute myeloid leukemia represents a critical clinical challenge, occurring in 3050% of patients and correlating with adverse prognosis . While bone marrow remains the primary diseasesite, leukemic cells colonize diverse tissue environments—each presenting unique biochemical landscapes, oxygentensions, and immune contexts. Understanding how malignant cells adapt to these heterogeneous niches isessential for rational therapeutic design.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18168135

Author: Stefan, Ionut Alexandru

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7119477436

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