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Environmental regulation, air pollution, and cognitive function among middle-aged and older adults in China: A quasi-experimental study

Year: 2026

Type: article

Abstract: Environmental regulations may yield substantial health benefits, yet their impact on cognitive health remains inadequately understood. This study exaimed the cognitive health benefits of China’s Air Pollution Prevention and Control Action Plan (APPCAP) and explored the potential contribution of reduction in air pollution underlying this relationship. Data were derived from four waves (2011–2018) of the China Health and Retirement Longitudinal Study (CHARLS). The intervention and control groups were designated based on provincial-level mandated air pollution reduction targets under APPCAP (>5 % vs. ≤ 5 %). Cognitive function was assessed using standardized questionnaires measuring episodic memory and mental status at each wave. Ambient fine particulate matter (PM 2.5 ) and self-reported household solid fuel use for cooking were evaluated as indicators of outdoor and indoor air pollution, respectively. A difference-in-difference (DID) approach was employed to assess APPCAP’s impact on cognitive function, with changes in outdoor and indoor air pollution investigated as potential mechanisms. Heterogeneity in policy effects across sociodemographic groups was also analysed. Implementation of the APPCAP was associated with significant improvements in cognitive function ( β coefficient = 0.72, 95 % CI: 0.50, 0.94). Significant reductions in ambient PM 2.5 concentrations and household solid fuel use contributed to 9.49 % and 6.47 % of the cognitive health improvements associated with the APPCAP, respectively. Subgroup analyses revealed stronger protective effects among middle-aged adults, rural residents, and individuals with lower educational attainment. This study provides evidence that environmental regulations could effectively protect cognitive health through reductions in air pollution exposure. • APPCAP protected cognitive function in middle-aged and older Chinese adults. • Reductions in PM 2.5 and solid fuel use partially explained the cognitive benefit. • Effects were greater for middle-aged, female, rural, and less-educated groups.

Source: Ecotoxicology and Environmental Safety

DOI: 10.1016/j.ecoenv.2025.119626

Authors: Qi Zhao, Wei Jie Seow

Institutions: National University of Singapore, National University Health System

Language: English

Topic: Air Quality and Health Impacts

Subfield: Health, Toxicology and Mutagenesis

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,650