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GLP-1 Targeting Agents Impair Chemoimmunotherapy Effectiveness in Triple-Negative Breast Cancer

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Year: 2026
Type: preprint
Source: Research Square
DOI: 10.21203/rs.3.rs-8380296/v1
Authors: Joshua Gruber, Bethania Soares dos Santos, Maycon Marção, Ishrat Durdana, Brian Lee, Lavanya Vumma, Felipe Segato-Dezem, Hannah Chasteen, Song Zhang, Cheryl Lewis, Yan Peng, Alexis LeVee, Megan Wong, Joanne Mortimer, Heather McArthur, Philipp Scherer, Jasmine Plummer
Institutions: The University of Texas Southwestern Medical Center, St. Jude Children's Research Hospital, City Of Hope National Medical Center, City of Hope
Language: English

Topic: Breast Cancer Treatment Studies
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: AstraZeneca, Cancer Prevention and Research Institute of Texas, University of Texas Southwestern Medical Center, Ovarian Cancer Research Alliance, National Institutes of Health, National Cancer Institute
Awards: G3605267802, G6361887759, Recruitment of First-Time, Tenure-Track Faculty Members, Molecular mechanisms and therapeutic principles of VISTA+ triple-negative breast cancers, UT Southwestern Medical Center Simmons Comprehensive Cancer Center
OpenAlex ID: W7119481975
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Cited by: 3
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