Palladium/Copper Dual Catalysis in the Cross‐Coupling of Stable Diphosphine Disulfides and Terminal Alkynes in the Presence of Molecular Iodine
Year: 2026
Type: article
Abstract: ABSTRACT A rapid, convenient, one‐pot strategy for the synthesis of 1‐alkynylphosphine sulfides has been developed via Pd/Cu‐catalyzed cross‐coupling between terminal alkynes and P V –I interelement compound generated from the reaction with air‐ and moisture‐stable tetraphenyldiphosphine disulfides and molecular iodine. The transformation proceeds smoothly under mild conditions, completing within 1 h and affording high conversions to the corresponding 1‐alkynylphosphine sulfides in up to 90% yields. This method provides a practical, efficient route to 1‐alkynylphosphine derivatives using air‐ and moisture‐stable reagents, overcoming the limitations of previous strategies.
DOI: 10.1002/ajoc.70296
Authors: Yuki Yamamoto, Kota Iino
Institution: University of Yamanashi
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W7119493189