Peritonsillar Infiltration with Tramadol or Bupivacaine for Relief of Post-Tonsillectomy Pain in Children: A Randomized Clinical Study
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Background: Tonsillectomy, a routine paediatric procedure, is frequently accompanied by significant postoperative pain. Efficient pain control is essential to minimize morbidity. Peritonsillar infiltration of tramadol or bupivacaine may offer an effective localized analgesic alternative. Objective: To compare the analgesic efficacy and safety of tramadol and bupivacaine peritonsillar infiltration in children post-tonsillectomy. Methods: A randomized, double-blind, placebo-controlled study involving 90 children (aged 5–12 years) undergoing tonsillectomy was conducted. They were divided into: Group T: Tramadol 2 mg/kg (2 mL/tonsil) Group B: Bupivacaine 0.25% (2 mL/tonsil) Group C: Placebo (2 mL normal saline) Pain was assessed using the Wong-Baker FACES Pain Rating Scale at 1, 4, 8, 12, and 24 hours postoperatively. Secondary outcomes included time to first rescue analgesic and total analgesic consumption.
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7119493918
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