Work

Metal ligand cooperativity in the direct carboxylation and esterification of terminal alkynes by Cu-CNC complexes bearing 2,6-lutidine linkers

Year: 2026

Type: article

Abstract: )*] complex. This marks the first time such data have been reported for dearomatized-metal-CNC systems. To establish mechanistic details of the reaction, we performed stoichiometric reactions and characterized products with a variety of NMR methods. Combined with supporting computational studies, the work yields several new CNC-supported copper intermediates, including copper-styrenyl, copper-acetylide, and copper-propiolate. While the reactive and labile nature of some of these intermediates precludes their solid-state characterization, DFT-computed structures are consistent with spectroscopic characterization.

Source: Chemical Science

DOI: 10.1039/d5sc08379f

Authors: Nick Back, Emylie Guthrie, Chengxu Zhu, Sam P. de Visser, Laleh Tahsini

Institutions: Oklahoma State University, University of Manchester

Language: English

Topic: Organometallic Complex Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: Oklahoma Center for the Advancement of Science and Technology

Award: G4571851957