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12 01 Base Architecture Gastric Adenocarcinoma Intestinal Type

Year: 2026

Type: article

Abstract: Intestinal-type gastric adenocarcinoma (IGA) represents50-60% of gastric cancers, characterized by glandular differentiation and chronic inflammatory microenvironment. Unlike diffuse-type gastric cancer, IGA exhibits preserved cellular cohesion and distinct metabolic zonationdriven by vascular heterogeneity . Current therapeuticapproaches target isolated pathways (HER2, PD-1), yet5-year survival remains 30% for advanced disease. This framework tries to model the carcinomas dynamic and architecture, that can lead to varios simulations depending on paramteres of how the carconoma responds and adapts in various scenarios and constraints.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18166075

Author: Stefan, Ionut Alexandru

Language: English

Topic: Gastric Cancer Management and Outcomes

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7119508696

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