Work

Design, Synthesis and In vitro Assessment of di-/tri-methoxy-aryl-substituted mono-spiro-1,2,4,5-tetraoxanes for Antiplasmodial and Anticancer Use

Year: 2026

Type: preprint

Abstract: A library of novel non-symmetrical di-/tri-methoxy-aryl-substituted mono-spiro-1,2,4,5-tetraoxanes has been prepared from complex-catalysed two-step one-pot direct oxidation approach and their in vitro antiplasmodial and cytotoxic potentials have been assessed against the chloroquine resistant FcB1 strain of Plasmodium falciparum, HeLa, A549 and A2780 cancer cells.

DOI: 10.17605/osf.io/9v3zs

Authors: Mohit Kumar Tiwari, Małgorzata Kucinska, Zgoła-Grześkowiak, Agnieszka, Raeispour, Marziyeh, Murias, Marek, Grellier, Philippe, Gośliński, Tomasz Adam, Łukasz Marczak

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7119511598

Cites:

Cited by:

Related to: