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Table S1 from RAS(ON) Multiselective Inhibition Drives Antitumor Immunity in Preclinical Models of NRAS-Mutant Melanoma

Year: 2026

Type: other

Abstract: Supplemental Table 1: Melanoma cell lines with Q61 and G13 NRAS mutations are sensitive to RAS(ON) multi-selective inhibition in vitro. RMC-7977 potently inhibited the growth of the mouse OSUMMER 1, 2, 3, 4, 5, 9, 11, 12 and 13 cells, SW1 and IPC298 cells with a similar potency.

DOI: 10.1158/2326-6066.31028303

Authors: Larissa Anastacio Da Costa Carvalho, Nataliya Tovbis Shifrin, Manali S. Phadke, Michael F. Emmons, Ximo Pechuan-Jorge, Felix Mbuga, Oscar E. Ospina, Christopher Chow, Lillian Seu, Olivia L. Rose, Aparna Hegde, Nikhil I. Khushalani, Elsa Quintana, Keiran S.M. Smalley

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7119512652

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