Work

Selective Oxidation of Tertiary C–H Bonds in Steroids Catalyzed by the Heterodimeric Fe(II)/α-Ketoglutarate-Dependent Oxygenase TlxI–J

Year: 2026

Type: article

Source: Journal of Natural Products

DOI: 10.1021/acs.jnatprod.5c01545

Authors: Huibin Wang, Yuben Qiao, Takahiro Mori, Ikuro Abe

Institutions: The University of Tokyo, State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei University, Japan Science and Technology Agency

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Takeda Science Foundation, Inoue Foundation for Science, Japan Agency for Medical Research and Development, New Energy and Industrial Technology Development Organization, Japan Society for the Promotion of Science, Fusion Oriented REsearch for disruptive Science and Technology

Awards: G4190789716, G4287169693, G6233850887, G6473414082, G7085967315, 薬用天然物の複雑骨格構築を担う新奇生合成酵素を用いた革新的次世代型天然物創薬

OpenAlex ID: W7119518339

FWCI: 5.572

Cites: 37

Cited by: 3

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