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Figure S11 from RAS(ON) Multiselective Inhibition Drives Antitumor Immunity in Preclinical Models of NRAS-Mutant Melanoma

Year: 2026

Type: other

Abstract: Supplemental Figure 11: CXCL signaling is altered in the presence of RMC-7977. (A) Heatmap showing the sources and receivers of CXCL signaling in the control, anti-PD1, RMC-7977 and anti-PD1 + RMC-7977 groups. (B) Violin plot showing the expression distribution of CXCL signaling ligands and receptors in the anti-PD1, RMC-7977 and anti-PD1 + RMC-7977 groups compared to control. Red represents the control and blue the indicated treated group.

DOI: 10.1158/2326-6066.31028336

Authors: Larissa Anastacio Da Costa Carvalho, Nataliya Tovbis Shifrin, Manali S. Phadke, Michael F. Emmons, Ximo Pechuan-Jorge, Felix Mbuga, Oscar E. Ospina, Christopher Chow, Lillian Seu, Olivia L. Rose, Aparna Hegde, Nikhil I. Khushalani, Elsa Quintana, Keiran S.M. Smalley

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7119533624

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