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Ovarian Sex Cord Stromal Tumor With Annular Tubules: A Rare Diagnosis in Young Women

Year: 2026

Type: article

Abstract: Ovarian sex cord-stromal tumor with annular tubules (SCTAT) is a rare neoplasm with distinct clinicopathological features in its sporadic and syndromic forms, the latter commonly associated with Peutz-Jeghers syndrome. Although imaging may suggest a sex cord-stromal origin, definitive diagnosis relies on histopathological examination. SCTAT primarily affects young women, and fertility-sparing surgery is typically preferred, often producing favorable outcomes. Nevertheless, the risk of recurrence remains significant, necessitating long-term follow-up. We report the case of an asymptomatic 36-year-old woman whose routine pelvic ultrasound detected a unilateral, solid, and vascularized right adnexal mass. Further imaging strongly suggested a stromal tumor, which was confirmed as SCTAT by histology after fertility-sparing laparoscopic salpingo-oophorectomy. No adjuvant treatment was given, and genetic testing ruled out Peutz-Jeghers syndrome. At six months postoperatively, there was no evidence of recurrence or tumor marker elevation. This case, the second reported SCTAT in Portugal, highlights the importance of multidisciplinary management and vigilant surveillance for optimal patient care.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.71829

Authors: Prescillia Marques, Thiago Vieira, Raquel Brodbeck Ilgenfritz, Dusan Djokovic

Institutions: Unidade Local de Saúde de Trás-os-Montes e Alto Douro, Hospital CUF Descobertas, University of Lisbon, Universidade Nova de Lisboa

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820