Year: 2025
Type: article
Abstract: Because of its exceptional combination of mechanical strength, corrosion resistance, and outstanding biocompatibility, titanium and its alloys continue to be essential in the development of cutting-edge biomedical implants. But choosing the right alloy system is not enough to provide maximum clinical performance; coordinated engineering of chemical composition, microstructure, and surface functioning is also necessary. This article offers a comprehensive summary of current developments in the design of non-toxic β-stabilized titanium alloys, thermomechanical processing to regulate microstructural characteristics, and nanoscale surface modification to improve biological responses. Stress shielding effects have been successfully mitigated by new alloy systems based on Nb, Ta, Zr, Mo, and Sn, which have shown notable gains in elastic modulus reduction, phase stability, and biomechanical compatibility. Strength, ductility, fatigue resistance, and changeable stiffness can be improved by precisely altering grain size, α/β phase distribution, and defect structures through microstructural optimization via solution treatment, aging, severe plastic deformation, and hot working. Anodization, acid and alkaline treatment, sol-gel deposition, and chemical vapor deposition are examples of complementary surface engineering techniques that create bioactive, nanostructured surfaces with antimicrobial or anti-inflammatory qualities, enhance corrosion resistance, and speed up osteointegration. A new paradigm in multifunctional titanium biomaterials that combine surface characteristics, microstructure, and composition optimization has emerged, one that may provide mechanical reliability with biological intelligence. This unified strategy will be useful in developing next-gen orthopedic and dental implants that integrate with the body more effectively, last longer, and provide superior clinical outcomes.
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W7120951119
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