Year: 2026
Type: article
Abstract: -diterpenoid alkaloids (1 and 2) and seven known ones (3-9) were isolated from Gymnaconitum gymnandrum. Their structures were elucidated based on spectroscopic data, including one- and two-dimensional nuclear magnetic resonance, infrared, high-resolution electrospray ionization mass spectrometry, and single-crystal X-ray diffraction analysis. These compounds were tested for their insecticidal activity and anti-chlamydial activity. The results show that compound 1 has the most insecticidal activity, with a median lethal concentration value of 0.73 ± 0.08 mg/mL; compound 3 exhibits an anti-chlamydia effect at a concentration of 100 µM.
Source: Chemistry & Biodiversity
Authors: Guo‐Li Li, Lei Zhang, Hong‐Ying Yang, Yi‐lin He, Tong Shen
Institution: Lanzhou Jiaotong University
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: green
Awards: G1405903861, G2188758765, G6715227653
OpenAlex ID: W7121233100
