Importance of basic science and research training for the future generation of cardiologists.
Year: 2026
Type: article
Abstract: Advances in the battle against cardiovascular diseases depend upon continuously translating emerging scientific knowledge from preclinical studies and clinical trials into innovative and effective therapeutic strategies. Over the past three decades, molecular and cellular biology have undergone a profound transformation, and large-scale, single-cell, and multi-omics studies have enabled investigations on cardiac disease mechanisms with unprecedented precision. However, these rapid advancements have also contributed to a divergence between the needs and aspirations of basic researchers and those of clinical scientists and practicians, to the detriment of discovery science, precision medicine, and cardiovascular healthcare. The present document highlights the importance of education and training in overcoming the gap between discovery and clinical science, by promoting a common language aimed at designing more translationally relevant and impactful discovery science. To achieve this aim, multidisciplinary efforts will be required to better define learning objectives within training programmes, including education in discovery and clinical sciences, promotion of specific mentorship paths, collaborative research efforts, promotion of equality, diversity, and inclusion, and protection of research time and activity within academic, clinical, and research careers.
Source: Apollo (University of Cambridge)
DOI: 10.17863/cam.124622
Authors: Chiva-Blanch, Gemma, Liehn, Elisa, Andreadou, Ioanna, Barc, Julien, Brundel, Bianca JJM, Davidson, Sean M, Elliott, Perry, Evans, Paul C, Giricz, Zoltan, Gladka, Monika, Gollmann-Tepeköylü, Can, Kleinbongard, Petra, Krieg, Thomas, Linde, Cecilia, Lüscher, Thomas F, Guzik, Tomasz, Maguy, Ange, McDonagh, Theresa, Paillard, Melanie, Parma, Radoslaw, Pesce, Maurizio, Pompilio, Giulio, Rubini, Maria, Streckfuss-Bömeke, Katrin, Thielmann, Matthias, Tocchetti, Carlo G, Van Linthout, Sophie, Vardas, Panagiotis, Vranckx, Pascal, Wojta, Johann, Perrino, Cinzia
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Deutsches Zentrum für Herz-Kreislaufforschung, Agence Nationale de la Recherche, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Lunds Universitet, Odense Universitetshospital, Turun Yliopisto, Universidade de Coimbra, Università di Bologna, Turun Yliopistollinen Keskussairaala, Lietuvos Sveikatos Mokslų Universitetas, Instituto de Salud Carlos III, Suomen Kardiologinen Seura
Awards: G1395533210, Role of the MICU1-MCU interaction in the Mitochondrial Ca2+ Regulation during ischemia-reperfusion injury, Vesículas extracelulares y variantes genéticas como biomarcadores de aterosclerosis preclínica significativa e independiente del riesgo cardiovascular clínico., Addressing sex inequalities in the management of cardiogenic shock complicating acute myocardial infarction, Unraveling the complexity of atrial fibrillation for CAR T therapy., G8780388766
OpenAlex ID: W7121376889
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