Year: 2026
Type: article
Abstract: MEIOC, which is part of an RNA-binding complex, regulates meiosis-associated genes through STRA8-MEIOSIN during spermatogenesis. In their work, Maria Mikedis and colleagues show that MEIOC initiates the mitosis-to-meiosis transition in mammalian oocytes by repressing the mitotic cyclin CCNA2 and promoting the STRA8-MEIOSIN pathway. To learn about their work, we spoke to the first author, Esther Ushuhuda, and the corresponding author, Maria Mikedis, Assistant Professor, UC Department of Pediatrics, Cincinnati Children's Hospital, USA.
Source: Development
DOI: 10.1242/dev.205440
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7122371714