Work

Chemo-enzymatic one-pot depolymerization of β-chitin

Year: 2026

Type: article

Abstract: over Pd-based nanoalloys, is used by a lytic polysaccharide monooxygenase (LPMO) to convert chitin into soluble oligosaccharide fragments. Our approach, which minimizes oxidative damage to the enzyme, eliminates the need for atom-inefficient and energy intensive approaches to chitin depolymerization, potentially achieving substantial environmental and economic savings. The simplicity of this chemo-catalyst/enzyme cascade has significant advantages for accessing chitin as a bio-carbon resource.

Source: Chemical Science

DOI: 10.1039/d5sc07429k

Authors: Joseph Brehm, Richard J. Lewis, Alan F. Scott, David J. Morgan, Thomas E. Davies, Nigel G. J. Richards, Graham J. Hutchings

Institutions: Cardiff University, Research Complex at Harwell, Foundation for Applied Molecular Evolution

Language: English

Topic: Studies on Chitinases and Chitosanases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Responsible consumption and production

Open Access status: diamond

Funders: Llywodraeth Cymru, Cardiff University, Wolfson Foundation, Norges Miljø- og Biovitenskapelige Universitet, Engineering and Physical Sciences Research Council, European Regional Development Fund

Awards: G412775704, G7308087707, G8561607855

OpenAlex ID: W7122566097

FWCI:

Cites: 50

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