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Successful Management of Meningitis and Sepsis Due to Multidrug-Resistant Elizabethkingia meningoseptica in an Infant

Year: 2026

Type: article

Abstract: We report a case of a two-month-old male infant, born prematurely, who initially presented with fever, irritability, and elevated inflammatory markers. He was then diagnosed with Elizabethkingia meningoseptica meningitis and sepsis. Treatment included intravenous levofloxacin, ampicillin, and cefotaxime. Despite the bacterium’s multidrug resistance and high reported morbidity and mortality rates, the patient made a full recovery with no complications at discharge or follow-up. This case demonstrates the challenges in treating E. meningoseptica infections and highlights the potential clinical efficacy of antibiotic regimens that may not align with standard susceptibility testing.

Source: Cureus

DOI: 10.7759/cureus.101368

Authors: Minat Allah Alhusami, Shahad Alshamsi, Amina Mujahid, Arun Jayaraman

Institutions: Mohammed Bin Rashid University of Medicine and Health Sciences, Mediclinic City Hospital

Language: English

Topic: Bacterial Infections and Vaccines

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7122623503