Work

Composite materials based on metal-organic frameworks loaded with effective therapeutic components for promoting wound healing

Year: 2026

Type: article

Abstract: Wound repair has long been a challenging area in medical research and clinical treatment. The unique properties of MOFs(metal organic frameworks), including their highly tunable porous structures, significant specific surface area, and ease of functionalization, make them particularly useful for drug delivery applications. MOFs can efficiently load a variety of therapeutic agents, such as small molecule drugs, biomolecules, gas molecules, nanoparticles, and photosensitizers, enabling slow, controlled release and precise, targeted delivery of these substances. Moreover, MOFs can be combined with other materials to create multifunctional wound dressings. This review introduces the mechanisms and advantages of MOFs loaded with therapeutic agents and provides an overview of the latest research progress in composite materials based on MOFs loaded with effective therapeutic components for wound treatment.

Source: Frontiers in Materials

DOI: 10.3389/fmats.2025.1713264

Authors: Shaogeng Wang, Fuchao Huang, Junbo Wang, Xiaomin Wu, Xiaohua Pan

Institutions: Shenzhen University, Guangdong Medical College, ShenZhen People’s Hospital, Shenzhen Bao'an District People's Hospital

Language: English

Topic: Wound Healing and Treatments

Subfield: Rehabilitation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801