Analysis of Salivary Levels of Titanium and Nickel Levels among Patients Treated with Dental Implants Therapy
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: The present investigation aimed to evaluate salivary concentrations of titanium and nickel in individuals subjected to endosseous implant therapy. Materials and Methods: A total cohort of 100 participants was recruited. Among them, 50 individuals constituted the control cohort without prosthetic intervention, whereas the remaining 50 individuals had undergone placement of a single osseointegrated implant fixture. Unstimulated whole saliva samples were collected from each subject and subsequently analyzed for trace metal quantification of titanium and nickel. The recorded data were systematically tabulated, and statistical interpretation was performed utilizing SPSS analytical software. Results: The study group comprised 69 male and 31 female participants. Subjects rehabilitated with dental implants demonstrated mean salivary titanium concentration of 123.54 ± 258.02 μg/L and mean salivary nickel concentration of 53.97 ± 16.09 μg/L. In comparison, the control cohort without implant placement exhibited relatively diminished levels of both metallic ions. Conclusion: The outcomes of this investigation indicate that salivary titanium and nickel concentrations are significantly elevated in patients treated with endosseous dental implants compared to individuals without such prosthetic rehabilitation.
Authors: Sahil Sarin, Sipra Sarin, Deepa Venkatesh, Kartiki Mehrotra, Abhidi, Shreanshi Jolly
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $250
OpenAlex ID: W7122845259