Work

Damage to Polymer Coatings on Microguidewire Tips through Shaping and J-wiring for Optimizing Flow Diverter Deployment: A Scanning Electron Microscopy Study

Year: 2026

Type: article

Abstract: Achieving adequate wall apposition is a crucial technical goal when deploying flow diverters to treat wide-neck cerebral aneurysms. The socalled J-wiring technique is a common method used to optimize flow diverter wall apposition. However, the frictional interaction between the shaping device and the microguidewire tip during the formation of the J-loop, as well as the interaction between the J-loop and the flow diverter during J-wiring, may potentially cause damage to the guidewire's coating. Three frequently used guidewires were tested in vitro in a silicone aneurysm model. Manual J-shaping of guidewire tips, along with the J-wiring technique (including J-shaping), caused damage to the surface coating of guidewires, as observed by scanning electron microscopy. Therefore, both mechanisms may contribute to the generation of polymer micro-fragments in patients treated with flow diversion.

Source: Neurointervention

DOI: 10.5469/neuroint.2025.01130

Authors: Rasmus Holmboe Dahl, Esben Thormann, René Wugt Larsen, Goetz Benndorf

Institutions: Copenhagen University Hospital, Rigshospitalet, Technical University of Denmark, Baylor College of Medicine

Language: English

Topic: Intracranial Aneurysms: Treatment and Complications

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Faculty of Health and Medical Sciences, University of Western Australia, Det Sundhedsvidenskabelige Fakultet, Københavns Universitet