Work

Determination of Histamine in Tuna Fish by a Rapid and Green DART‐TQ MS Method

Year: 2026

Type: article

Abstract: This application note describes the development of a rapid and sustainable screening method for the detection of histamine (HIS) in food, representing a key biogenic amine and safety marker in tuna, based on the coupling between an ambient soft ionization source and a triple quadrupole mass spectrometer (DART-TQ-MS/MS). The method requires minimal sample preparation and enables the targeted quantification of HIS through optimized MRM transitions (112.2 → 95.0 and 112.2 → 68.1 m/z). The DART-TQ-MS/MS platform offers an efficient first-line tool providing rapid preliminary control in complex food matrices before confirmatory analysis.

Source: Journal of Mass Spectrometry

DOI: 10.1002/jms.70027

Authors: Anna Luparelli, William Matteo Schirinzi, Laura Quintieri, Alexandre Verdu, Linda Monaci

Institutions: Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Research Council, Institute of Sciences of Food Production, Bruker (France)

Language: English

Topic: Mass Spectrometry Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,430

OpenAlex ID: W7123336529

FWCI:

Cites: 19

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