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Novel Pyridopyrazine Derivatives as Inverse Agonists of the G Protein-Coupled Receptor 6

Year: 2026

Type: editorial

Abstract: High Resolution Image Download MS PowerPoint Slide This patent highlight describes the development and evaluation of novel pyridopyrazine analogs as potent inverse agonists for G protein-coupled receptor 6 (GPR6). It discloses synthetic methods and pharmacological properties of these new GPR6 modulators.

Source: ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.5c00748

Authors: Yinlong Li, Steven H. Liang

Institutions: Emory University, Georgia Institute of Technology, The Wallace H. Coulter Department of Biomedical Engineering

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W7123336549

Cites: 7

Cited by: 1

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