Work

Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c02570

Authors: Xingxing Cheng, Zheqi Hu, Huihuan Mao, Ziyue Li, Zhen Wang, Yixuan Tang, Shihui Huang, Yujing Huang, Chunxiang Yin, Hanxi Xing, Sijia Chen, Yuhan Jiang, Ting Hu, Jiawen Zuo, Wenxin Yan, Hongfeng Gu, Ping Wei, Yungen Xu, Qihua Zhu, Yi Zou

Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine

Language: English

Topic: Cancer-related gene regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National College Students Innovation and Entrepreneurship Training Program

Award: G673532321

OpenAlex ID: W7123339855

FWCI: 7.368

Cites: 30

Cited by: 4

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