Motion‐ and Field‐Robust Mesoscopic Whole‐Brain T2*‐Weighted Imaging at 7 and 11.7 T Using Servo Navigation
Year: 2026
Type: article
Abstract: PURPOSE: -weighted human brain imaging using servo navigation at ultra-high fields up to 11.7 T. METHODS: MR-based servo navigators were integrated into a segmented 3D-EPI sequence to allow for prospective correction of involuntary head motion and first-order shim changes. Seven subjects were scanned with whole-brain protocols at 0.3 mm isotropic resolution with and without correction at 7 and 11.7 T. Validation was performed on detailed brain vasculature in scans with involuntary motion. RESULTS: Blurring of small veins was reduced by servo navigation for all subjects and across field strengths. In case of involuntary large motion, the method preserved image quality, while uncorrected motion led to severe artifacts. In case of microscopic motion, reduced blurring and shading in the frontal lobe demonstrate the additional benefit of prospective field drift correction. CONCLUSION: -weighted imaging under realistic motion and field changes within 5.5 to 11 min scan time at 11.7 and 7 T.
Source: Magnetic Resonance in Medicine
DOI: 10.1002/mrm.70251
Institutions: University of Bonn, German Center for Neurodegenerative Diseases, University of Zurich, ETH Zurich, Institute for Biomedical Engineering, Centre National de la Recherche Scientifique, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, Université Paris-Saclay, Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields, University of Glasgow, University of Freiburg, University Medical Center Freiburg
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,680
OpenAlex ID: W7123342413