Differential socioeconomic, psychosocial, and behavioral factors associated with psychological distress and uncontrolled blood pressure among women with and without HIV in the US
Year: 2026
Type: article
Abstract: Introduction Women with HIV (WWH) have a higher risk of hypertension compared to women without HIV (WWoH). Exposure to adverse socioeconomic (e.g., area level deprivation) and psychosocial factors (e.g., stigma, inadequate social support) may contribute to inequities in hypertension through their influence on health behaviors (e.g., substance use, diet, physical activity) and psychophysiological (e.g., stress) responses. Methods We examined the association between socioeconomic and psychosocial factors, psychological distress, and current uncontrolled blood pressure among WWH ( n =998) and WWoH ( n =353) enrolled in the Women’s Interagency HIV Study (WIHS) at a single visit between April and September 2019. Results Socioeconomic and psychosocial factors were similar among WWH and WWoH. Among WWH and WWOH, 50.2% had current uncontrolled blood pressure, defined as a systolic blood pressure ≥130 mmHg or diastolic pressure ≥ 80 mmHg at the time of the study visit. Among WWH, socioeconomic, psychosocial, and behavioral factors explained 3% of the variance in blood pressure with self-reported health risk behaviors ( r =0.15), and use of antihypertensive medication ( r =0.09) had weak to moderate impact. Among WWoH, socioeconomic, psychosocial, and behavioral factors explained 10% of the variance in blood pressure, with self-reported health risk behaviors ( r =0.19), use of antihypertensive medication ( r =0.19), area-level social vulnerability ( r =-0.17), and social support ( r =0.16) demonstrating weak to moderate impacts. Discussion Tailored interventions that address socioeconomic and psychosocial stressors at the individual and societal levels may improve outcomes and reduce disparities in uncontrolled blood pressure.
Source: Frontiers in Medicine
Authors: Jenni M. Wise, Emily B. Levitan, Elizabeth A. Jackson, Paul Muntner, Edgar T. Overton, Liang Shan, Jessica Blair, Andres Azuero, Jennifer H. McCarty, Maria L. Alcaide, David B. Hanna, Andrew Edmonds, Sheri D. Weiser, Seble G. Kassaye, Aruna Chandran, Gina Wingood, Deborah Konkle-Parker, Tracey E. Wilson, Kathleen M. Weber, Mirjam-Colette Kempf
Institutions: University of Alabama at Birmingham, University of Miami, Albert Einstein College of Medicine, University of North Carolina at Chapel Hill, University of California, San Francisco, Georgetown University, Johns Hopkins University, Columbia University, University of Mississippi Medical Center, SUNY Downstate Health Sciences University, Hektoen Institute
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
Funders: Organization for Autism Research, Indiana Clinical and Translational Sciences Institute, Mucolipidosis IV Foundation, Georgia Clinical and Translational Science Alliance, National Institutes of Health, Center for AIDS Research, University of Washington, University of California, San Francisco, Center for AIDS Research, University of Alabama at Birmingham, National Institute on Alcohol Abuse and Alcoholism, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Cancer Institute, National Institute on Deafness and Other Communication Disorders, National Institute of Nursing Research, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, Fogarty International Center, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Dental and Craniofacial Research, National Center for Advancing Translational Sciences, National Institute on Minority Health and Health Disparities, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Center for AIDS Research, University of North Carolina at Chapel Hill, Clinical and Translational Science Institute, University of California, Los Angeles
Awards: G1034546755, G1090173496, G12089860, G1296759572, G1557182087, G1787625665, G183157880, G1849940085, G1913134163, G1972383081, G2008237588, G2127051194, G2334180555, G255204022, G2908277772, G30074556, G311558797, G3242306066, UAB Institutional Career Development Program in HIV-Related Heart, Lung, Blood and Research, G3630727822, G3671922257, G3869857964, G4016133911, G4044828089, G4535678174, G456742281, G4769057925, G5078796989, G521591464, G5525419549, G5691055145, G5699974340, G5900455136, G6745172908, G6990385686, G775892330, G7760075911, G7807729167, Johns Hopkins Institute for Clinical and Translational Research, G9000016284, G9000030090, G9000030772, G9000031392, G9000039899, G9000041916, G9000080293, G9000082816, G9000099115, G9000102070, G9000108991, G9000146713, G9000343736, UAB Center for AIDS Research (CFAR), G929137571, G940002362, G94475886
OpenAlex ID: W7123348705