Work

Translational Suppression of KRAS and NRAS via RNA G-Quadruplex-Targeting Small Molecules for Colorectal Cancer Therapy

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c03088

Authors: Bo-Xin Zheng, Ze-Xin Chen, Ya-Kun Wang, Jia-Peng Dong, Meng-Ting She, Ying-Ying Zheng, Yao-Xun Zeng, Wen-De Zheng, Wei Long, Wing-Leung Wong

Institution: Hong Kong Polytechnic University

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Research Grants Council, University Grants Committee, Hong Kong Polytechnic University

Awards: G4221322947, Development of small molecules selectively targeting mitochondrial mRNA G-quadruplexes as an anticancer strategy, G6488883359

OpenAlex ID: W7123349180

FWCI: 5.572

Cites: 59

Cited by: 3

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