Work

MTFP1 preserves β-cell cristae structure and bioenergetics to ensure insulin release and glucose homeostasis

Year: 2026

Type: preprint

Source: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.64898/2026.01.12.697845

Authors: Sunehera Sarwat, Rosa Alén, Zhiyi Wu, Chuyue Zhang, Michael Paszek, MingMing Yang, Giada Ostinelli, Alina Mihalovits, Bell Baker, Timothy Wai, Guy A. Rutter, Tristan A. Rodriguez, Aida Martinez-Sanchez

Institutions: Hammersmith Hospital, Imperial College London, Centre Hospitalier de l’Université de Montréal, Université de Montréal, Centre National de la Recherche Scientifique, Institut Pasteur, Université Paris Cité, Biologie cellulaire physiologique et pathologique, Nanyang Technological University, McGill University Health Centre, Research Institute of the McGill University Health Centre, McGill University

Language: English

Topic: Pancreatic function and diabetes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Canadian Institutes of Health Research

Award: Spatio-temporal dynamics of immune and non-immune islet injury in Type 1 Diabetes

OpenAlex ID: W7123353198

Cites: 75

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