Work

Clinical utility of serial plasma cell-free DNA metagenomic next-generation sequencing assays

Year: 2026

Type: article

Study design: Observational Study

Abstract: This single center retrospective observational study of serial plasma metagenomic next-generation sequencing testing shows that >95% of serial testing was without meaningful clinical impact. Only 5/173 cases were adjudicated as having significant clinical impact.

Source: Infection Control and Hospital Epidemiology

DOI: 10.1017/ice.2025.10390

Authors: Ishminder Kaur, Bennett Shaw, Ashrit Multani, Sanchi Malhotra, Huan Vinh Dong, Christy Lukose, Kavitha Prabaker, Tawny Saleh, Young Bo Sim, Christopher N. Tymchuk, Daniel Z. Uslan, Helen Zhou, Timothy F. Brewer, Shangxin Yang

Language: English

Topic: Bacterial Identification and Susceptibility Testing

Subfield: Clinical Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,550

Funder: National Institutes of Health

OpenAlex ID: W7123361485

FWCI: 4.363

Cites: 11

Cited by: 1

Related to: