Multidisciplinary guidelines on renal replacement therapy in intensive care medicine
Year: 2026
Type: article
Abstract: BACKGROUND: Renal replacement therapy (RRT) is frequently used in critically ill patients with acute kidney injury (AKI). Here, we provide guidelines for the management of RRT in critically ill patients on the intensive care unit (ICU). METHODS: We convened a systemic literature research and a Delphi process with a bi-national multidisciplinary consensus panel including 22 clinicians of 12 different German-speaking societies (Germany and Austria) with expertise in RRT. This structured guideline process was the basis for the evidence-based statements and recommendations. RESULTS: We identified seven clinical areas needing guidance: (1) start, (2) modality (diffusion and convection), (3) continuous/ intermittent, (4) anticoagulation, (5) dose (6) pharmacotherapy, (7) stopping criteria. The consensus produced 73 statements and recommendations regarding key clinical areas, the most important 47 statements and recommendations are summarized in this overview. CONCLUSIONS: This evidence-based bi-national guideline should provide physicians with guidance for delivering best practice to critically ill patients with a dialysis-dependent AKI.
Source: Critical Care
Authors: Melanie Meersch-Dini, Mariam Abu-Tair, Matthias Bayer, Alexander Brinkmann, Romuald Bellmann, Frank Brunkhorst, Florian Custodis, David Czock, Otto Frey, Jan Galle, Carsten Hermes, Michael Joannidis, Stefan John, Achim Jörres, Thomas Kerz, Detlef Kindgen-Milles, Martin Koczor, Rainer Kram, Martin Kuhlmann, Michael Oppert, Georg Schlieper, Michael Schmitz, Alexander Zarbock, Carsten Willam
Institutions: University of Münster, University Hospital Münster, Asklepios, Innsbruck Medical University, Universität Innsbruck, Jena University Hospital, Klinikum Saarbrücken, Heidelberg University, University Hospital Heidelberg, Klinikum Lüdenscheid, HAW Hamburg, Nuremberg Hospital, Witten/Herdecke University, University Medical Center of the Johannes Gutenberg University Mainz, Düsseldorf University Hospital, Heinrich Heine University Düsseldorf, Klinikum im Friedrichshain, Klinikum Ernst von Bergmann, HMU Health and Medical University, Städtisches Klinikum Solingen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen
Language: English
Topic: Acute Kidney Injury Research
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,190
OpenAlex ID: W7123420086