Work

Effects of cyclic yoga on selected metabolic and hepatic parameters in diabetic women with fatty liver diseases: A clinical trial

Year: 2026

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: • Cyclic yoga significantly improved glycemic, lipid, and hepatic parameters in women with T2DM and NAFLD. • Eight weeks of cyclic yoga reduced body weight, BMI, and waist circumference. • Liver enzymes and fatty liver grade improved following cyclic yoga intervention. • Yoga enhanced insulin sensitivity and cardiometabolic health outcomes. • Cyclic yoga is a safe, low-cost therapy for managing T2DM with NAFLD. Type 2 diabetes mellitus and non-alcoholic fatty liver disease increase cardiometabolic risk. This randomized controlled trial assessed the effects of cyclic yoga, a structured asana sequence, on anthropometric, glycemic, lipid, and hepatic parameters in overweight women with both conditions. Forty overweight women (mean age 50.5 ± 5.5 years) with type 2 diabetes and non-alcoholic fatty liver disease were randomized to either an eight-week cyclic yoga intervention (three sessions/week) or a control group maintaining usual activities. Pre- and post-intervention, fasting blood glucose, glycated hemoglobin, insulin resistance, lipid profile, liver enzymes (alanine aminotransferase, aspartate aminotransferase), anthropometric parameters were measured and analyzed using repeated measures analysis of variance. The cyclic yoga group showed significant reductions in fasting blood glucose, glycated hemoglobin, insulin resistance, triglycerides, low-density lipoprotein cholesterol, alanine aminotransferase, aspartate aminotransferase, weight, body mass index, hip circumference, waist circumference, with increased high-density lipoprotein cholesterol compared to control group. Cyclic yoga appears to improve glycemic control, lipid profiles, liver enzymes, and anthropometric indices in women with type 2 diabetes mellitus and non-alcoholic fatty liver disease. These findings suggest that cyclic yoga may be a safe, practical, and cost-effective complementary therapy to improve metabolic and hepatic health in this high-risk population, although larger and longer term studies are warranted.

Source: Journal of Clinical & Translational Endocrinology

DOI: 10.1016/j.jcte.2026.100431