Work

Waxy nodule on the nasal ala post-trauma: clinical presentation and surgical resolution

Year: 2026

Type: article

Abstract: Primary cutaneous nodular amyloidosis is a rare type of amyloidosis where the deposition of amyloid is limited to the skin, and unlike macular or lichenoid amyloidosis, traumatic epidermal damage is not believed to play an etiopathogenic role. Must be studied and followed-up, because it is associated with Sjögren’s syndrome and progression to systemic amyloidosis has been reported. Dermoscopy findings are yellow-orange background, bright white lines, and linear and serpiginous telangiectasias. The treatment is surgical excision, although various treatment options have been described. We report a unusual case of primary cutaneous nodular amyloidosis secondary to local trauma on the nose.

Source: Revista Medicina Cutánea Ibero-Latino-Americana

DOI: 10.24875/mcute.m25000051

Authors: Valeria Alfaro-Fierro, Felipe Alcayaga-de la Ribera, Pamela Vergara-Pinto, Claudio Escanilla-Figueroa, Laura Segovia González

Institutions: University of Chile, Hospital Barros Luco-Trudeau

Language: English

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7123571211