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Guillain–Barré syndrome following dengue infection in an adult patient: a case report

Year: 2026

Type: article

Abstract: • Dengue infection can rarely trigger Guillain–Barré syndrome in adults • Early recognition of post-dengue GBS is critical in endemic regions • Timely IVIG and intensive care support can significantly improve outcomes Dengue fever is a viral disease that presents with a wide range of neurological features. Although less frequent, Guillain–Barré Syndrome (GBS) is a life-threatening, postinfectious neurological sequela. A 44-year-old Bangladeshi male presented with flaccid quadriplegia during the recovery phase of serologically confirmed dengue fever. Cerebrospinal fluid (CSF) analysis showed albuminocytologic dissociation. The patient was treated with intravenous immunoglobulin therapy and supportive measures, including mechanical ventilation. His condition improved after 14 days of critical care. This case underscores the importance of maintaining a high index of suspicion for GBS in patients with dengue fever in endemic regions. Early diagnosis and multidisciplinary management are essential for better outcomes.

Source: Brain Disorders

DOI: 10.1016/j.dscb.2026.100306