Work

Indolent systemic mastocytosis with response to phototherapy in a patient with other non-hematologic neoplasms: a therapeutic challenge

Year: 2026

Type: article

Abstract: Mastocytosis is a rare clonal hematopoietic disorder characterized by the proliferation of neoplastic mast cells in the skin or other organs, including the bone marrow. It is classified into cutaneous, systemic, and mast cell sarcoma. Treatments focus on symptoms control or eliminating mast cells, with KIT inhibitors like midostaurin and avapritinib being effective therapies. Phototherapy has proven effective in symptomatic control in indolent systemic mastocytosis as in the presented case, improving quality of life.

Source: Revista Medicina Cutánea Ibero-Latino-Americana

DOI: 10.24875/mcute.m25000046

Authors: Diana G. Santamaría-Domínguez, Jimena Pérez-Rubio, Ilse Y. Osorio-Aragón, María E. Vega-Memije, Rosa M. Lacy-Niebla

Institution: Hospital General Dr. Manuel Gea Gonzalez

Language: English

Topic: Mast cells and histamine

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7123686198