Work

Computational Insights into the Interactions of Andrographolide Derivative SRJ09 with Histone Deacetylase for the Management of Beta Thalassemia

Year: 2026

Type: article

Abstract: Thalassemia is a group of anemias that result from inherited defects in the production of the beta chain of hemoglobin. It is stabilized by gamma globin, which combines to form fetal hemoglobin. One therapeutic approach is to target histone deacetylase (HDAC), which plays an important role in controlling beta thalassemia. This study sought to identify a natural inducer for treating this disease.

Source: Journal of Exploratory Research in Pharmacology

DOI: 10.14218/jerp.2025.00039

Authors: Soumya Khare, Tanushree Chatterjee

Institution: Kalyan Post Graduate College

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7123706445