Work

Inhibition of mTOR Enhances the Efficacy of Proteasome-Dependent Targeted Protein Degradation Approaches

Year: 2026

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-25-3941

Authors: Yang Liu, Yifeng Sun, Tian-Yu Song, Si-Yuan Ni, Yi-Sheng Pu, Yuan-Chen Chang, Wenrong Zhou, Zhen-Gang Peng, Jiajia Liu, Jun Shi, Wei Lu, Yong Cang

Institutions: ShanghaiTech University, Shanghai Jiao Tong University, Shanghai Ninth People's Hospital, Broad Institute, Harvard University, Massachusetts Institute of Technology, WuXi AppTec (China)

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Natural Science Foundation of China

Awards: G4029366870, G640357306, 小分子化合物劫持CRL4(CRBN)泛素连接酶降解WEE1的机制和功能研究, G7916709993

OpenAlex ID: W7123759718

FWCI: 1.842

Cites: 57

Cited by: 1

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