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Breast Adenoid Cystic Carcinoma: Recognizing a Rare Pathological Diagnosis

Year: 2026

Type: article

Abstract: Adenoid cystic carcinoma (ACC) of the breast is an exceedingly rare neoplasm. It exhibits a distinct dual cell population and a favorable prognosis despite its often triple-negative immunophenotype. We present a rare case of ACC diagnosed on core needle biopsy and confirmed in the resection specimen. The histopathological features, immunohistochemical profile, and relevant literature are discussed. This case emphasizes the importance of recognizing this rare entity when encountered in breast biopsies and the necessity for a collaborative, multidisciplinary approach to management.

Source: Cureus

DOI: 10.7759/cureus.101447

Authors: Prajakta Attarde, Shital Parekh

Institution: Milton Keynes Hospital

Language: English

Topic: Breast Lesions and Carcinomas

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7123909069