Work

From Chiral Separation to Asymmetric Synthesis: Route Scouting and Early Process Development of a Chiral Tetrahydrofuran–Pyrazolamine Intermediate of CDK2 Inhibitor RLY-2139

Year: 2026

Type: article

Source: Organic Process Research & Development

DOI: 10.1021/acs.oprd.5c00354

Authors: Seema Bag, Andre Lescarbeau, Allen Qinglin Che, Vishnu Karnati, Zhongbo Fei, Liyang Wang, Dehai Zhang, Jun Liu, Fan Jiang, Hai Wang, Gang Huang, Pengfei Shen, Jing Wang, Mingying Zhu, Yonghui Lu, Fanfan Meng, Baldip Kang, Surendra Singh, David Tschaen

Institution: Relay Therapeutics (United States)

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: closed

OpenAlex ID: W7124155494

FWCI: 1.871

Cites: 17

Cited by: 1

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