Work

The modulation of human motoneuron discharge patterns with contraction force in resistance- and endurance-trained individuals

Year: 2026

Type: article

Study design: Observational Study

Abstract: Physical training alters intrinsic motoneuron properties in reduced animal preparations, especially in neurons recruited at high excitation levels. Here, we show that individuals with a history of resistance or endurance training exhibit higher discharge rates that are more linear during forceful contractions. This likely reflects a more reciprocal/push-pull excitation-inhibition coupling, leading to greater net excitation to the motor pool that may contribute to greater force production observed in trained individuals.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00835.2025

Authors: Jakob Škarabot, Haydn Thomason, Benjamin M. Nazaroff, Christopher D. Connelly, Tamara Valenčič, Michael L. Ho, Kapil Tyagi, James A. Beauchamp, Gregory E. P. Pearcey

Institutions: Loughborough University, Memorial University of Newfoundland, Northwestern University, Carnegie Mellon University

Language: English

Topic: Muscle activation and electromyography studies

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Versus Arthritis, Natural Sciences and Engineering Research Council of Canada

Awards: G1851497914, It takes persistence to paint a PICture - the role of monoamines in producing human motor output, It takes persistence to paint a PICture - the role of monoamines in producing human motor output

OpenAlex ID: W7124158923

FWCI: 1.73

Cites: 71

Cited by: 1

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