Work

3.3V Sub-nA Voltage Gap Readout Circuit for Memristive Biosensing in Silicon Nanowire

Year: 2025

Type: conference-paper

Abstract: This paper proposes a sub-nanoampere readout circuit designed for fast and precise detection with silicon nanowire (SiNW) memristive biosensors via voltage gap measurement. Compared to traditional solutions, the proposed circuit, completed in 65 nm bulk CMOS process, significantly enhances sensitivity to the picoampere range and reduces measurement time from several minutes to one second. Comprehensive performance evaluation has been performed by considering SiNW models with different crossing behavior, including post-layout extraction (PEX) simulations. Accuracy of up to $20-30 \mathrm{mV}$ can be achieved on a particular prescaler configuration, which confirms circuit’s suitability for high-speed biosensing, real-time diagnostics and scalable integration into large sensor arrays.

Source: IEEE Biomedical Circuits and Systems Conference (BioCAS)

DOI: 10.1109/biocas67066.2025.00113

Authors: Dmitrii Semenov, Kapil Bhardwaj, Gian Luca Barbruni, Roman Sotner, Sandro Carrara, Pavel Horsky

Institutions: Brno University of Technology, Tampere University, University of Tampere, École Polytechnique Fédérale de Lausanne

Language: English

Topic: Analog and Mixed-Signal Circuit Design

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funder: National Science Foundation

OpenAlex ID: W7124174736

FWCI:

Cites: 16

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