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AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network.

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Year: 2026
Type: article
Source: Apollo (University of Cambridge)
DOI: 10.17863/cam.124725
Authors: Fadini, Alisia, Li, Minhuan, McCoy, Airlie J, Banjara, Suresh, Okumura, Hiroki, Napier, Eve, Fontana, Pietro, Khan, Amir R, Jovine, Luca, Terwilliger, Thomas C, Read, Randy J, Hekstra, Doeke R, AlQuraishi, Mohammed
Language: English

Topic: Protein Structure and Dynamics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: Wellcome Trust, Biotechnology and Biological Sciences Research Council, National Institute of General Medical Sciences
Awards: Phenix: Integrated algorithms for high quality models from crystallographic and cryo-EM data, Advanced likelihood-based methods in structural biology, Development of likelihood-based methods in structural biology
OpenAlex ID: W7124201682
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