Work

CellRefiner v1.0.0

Year: 2026

Type: software

Abstract: CellRefiner is a physical model-based method that integrates a scRNA-seq dataset with a paired spatial transcriptomics (ST) dataset to generate single-cell resolution in the imputed ST data. CellRefiner models cells as particles connected by forces, and then optimizes cell locations with spatial proximity constraints, gene expression similarity, and ligand-receptor interactions between cells.This is the release accompanying the publication.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.18263149

Authors: Bourgain-Chang, Eric, Kuang, Xiangyu, Cang, Zixuan, Nie, Qing

Institutions: University of California, Irvine, North Carolina State University

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7124273493

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Cited by: 1

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