Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Lasmiditan in tablet dosage form
Year: 2026
Type: article
Abstract: HPLC, in particular, offers high resolution, accuracy, and reproducibility, making it indispensable for routine quality control and advanced research applications. Method development in HPLC involves systematic selection and optimization of mobile phase composition, column chemistry, detection wavelength, and operational parameters to achieve reliable separation and quantification. Analytical method validation, guided by ICH and USP standards, ensures that developed methods meet essential criteria, including accuracy, precision, linearity, specificity, robustness, and sensitivity. Keywords: Lasmiditan, Development, RP-HPLC, Accuracy, linearity, Limit of detection (LOD) and Limit of quantification (LOQ).
Authors: Rahul Ramhari Darade, Sagar B Wankhede
Institution: JSPM University
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W7124291442