Work

Lipid Dependence of CYP3A4 Activity in Nanodiscs

Year: 2026

Type: article

Abstract: CYP3A4 is the main xenobiotic metabolizing enzyme in the human body, as it is in volved in metabolism of ~30% of drugs on the market as well as of many other compounds, from small molecules such as ethanol to large drugs such as erythromycin and cyclosporine [...].

Source: Biology

DOI: 10.3390/biology15020156

Authors: Ilia G. Denisov, Yelena V. Grinkova, Stephen G. Sligar

Institution: University of Illinois Urbana-Champaign

Language: English

Topic: Pharmacogenetics and Drug Metabolism

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,258