Work

Biomaterials for Improving Skin Penetration in Treatment of Skin Cancer

Year: 2026

Type: article

Abstract: Skin cancer is among the most common malignancies worldwide, posing a significant societal burden due to its increasing incidence and its limited responsiveness to conventional topical therapies. Treatment is challenged by the presence of the skin barrier which restricts drug penetration. This review discusses the structural and physiological challenges of topical delivery and summarizes efforts to develop functional biomaterials to enhance skin drug penetration. Important aspects to consider when developing formulation strategies, such as drug properties and release mechanisms, are discussed alongside current limitations and future perspectives.

Source: Journal of Functional Biomaterials

DOI: 10.3390/jfb17010039

Authors: Davide Secci, Andrew Urquhart, Vasileios Bekiaris, Katrine Qvortrup

Institution: Technical University of Denmark

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,258