Work

RasGRP1 agonists stimulate P-TEFb biogenesis via MEK-ERK-mTORC1 signaling to reverse HIV latency with minimal CD4 downregulation

Year: 2026

Type: preprint

Source: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.64898/2026.01.14.699500

Authors: Uri Mbonye, Ana Bellomo, Eleonora Elhalem, Lucia Gandolfi Donadio, Muda Yang, Amie Donner, Maria Julieta Comin, Jonathan Karn

Institutions: Case Western Reserve University, Consejo Nacional de Investigaciones Científicas y Técnicas, National Institute of Industrial Technology

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7124317876

Cites: 72

Cited by:

Related to: