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Discovery of Fluorinated Ultrapotent Chemogenetic Ligands for PET Imaging and Neural Modulation in Nonhuman Primates

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c02679
Authors: Sridhar Goud Nerella, Jeih-San Liow, Bing Li, Adrian E. S. Jenson, Matilah T. Pamie-George, Sami S. Zoghbi, Juan L. Gomez, Michael Michaelides, Chris Magnus, Scott M. Sternson, Barry J. Richmond, Mark A. G. Eldridge, Sanjay Telu, Robert B. Innis, Victor W. Pike
Institutions: National Institutes of Health, National Institute of Mental Health, National Institute of Mental Health, National Institute of Mental Health, National Institute on Drug Abuse, Newcastle University
Language: English

Topic: Radiopharmaceutical Chemistry and Applications
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Institute of Mental Health
Awards: G9000043886, G9000054429, G9000193048, Neural Mechanisms of Motivation and Reward
OpenAlex ID: W7124735733
FWCI:
Cites: 39
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