Residential mobility during pregnancy and birth outcomes in the United States: The environmental influences on Child Health Outcomes (ECHO) Cohort (2010–2019)
Year: 2026
Type: article
Abstract: PURPOSE: To examine factors associated with moving during pregnancy and impacts of assigning nSES at enrollment, delivery, or a time-weighted average on birth outcomes (birthweight, birthweight-for-gestational-age z-score, low birthweight, gestational age, small-for-gestational age, preterm birth). METHODS: We used data from the Environmental influences on Child Health Outcomes (ECHO) Cohort Study (2010-2019) with nSES data from the American Community Survey (ACS) matched by time and location to monthly residential histories. We used multivariable logistic models with Generalized Estimating Equations to identify factors associated with moving and quantify exposure misclassification in model estimates. RESULTS: Approximately 7 % of 15,376 participants moved at least once during pregnancy. Maternal age (OR: 0.97, 95 % CI: 0.95, 0.98) and other race vs. White (OR: 0.39, 95 % CI: 0.20, 0.80) were associated with lower odds of moving; lower neighborhood-level education (OR: 1.34, 95 % CI: 1.11, 1.62) and living in urban neighborhoods (OR: 3.03, 95 % CI: 1.39, 6.59) were associated with higher odds. Among movers, estimates between nSES and birth outcomes changed ≥ 16 % by address assignment; birthweight-for-gestational-age z-score was significant only when using nSES at delivery. CONCLUSION: Sociodemographic and nSES characteristics are associated with moving during pregnancy; movers may experience exposure misclassification and underestimated effects on birth outcomes.
Source: Annals of Epidemiology
Authors: Angela D’Adamo, Amii M. Kress, Rima Habre, Nissa Towe-Goodman, Michael R. Desjardins, Akram Alshawabkeh, Izzuddin M. Aris, Carlos A. Camargo, Kecia N. Carroll, Andrea E. Cassidy-Bushrow, Su H. Chu, Yolaine Civil, Alexandrea L. Craft, Lisa A. Croen, Sean Deoni, Viren Dsa, Anne L. Dunlop, Amy J. Elliott, Assiamira Ferrara, Jody M. Ganiban, Akhgar Ghassabian, Tina Hartert, Delma-Jean Watts, Margaret R. Karagas, Catherine J. Karr, Daphne Koinis-Mitchell, Michael Kramer, Cindy T. McEvoy, Hooman Mirzakhani, Thomas G. O’Connor, Wei Perng, Rebecca J. Schmidt, Uzma Shah, Irene Tung, Rosalind J. Wright, Emily A. Knapp
Institutions: Johns Hopkins University, University of Southern California, University of North Carolina at Chapel Hill, Northeastern University, Harvard University, Harvard Pilgrim Health Care, Massachusetts General Hospital, Icahn School of Medicine at Mount Sinai, Henry Ford Health, Brigham and Women's Hospital, Brown University, Kaiser Permanente Northern California, Gates Foundation, Emory University, University of South Dakota, George Washington University, New York University, Vanderbilt University Medical Center, Dartmouth College, University of Washington, Rhode Island Hospital, Oregon Health & Science University, University of Rochester Medicine, University of Rochester, University of Colorado Anschutz, University of California, Davis, California State University, Dominguez Hills
Language: English
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,820
Awards: Utah Children's Project, Childhood Allergy and the NeOnatal Environment (CANOE) ECHO Pediatric Follow-Up and New Enrollment, Mediators and Modifiers of Prenatal Environmental Exposures and Child Neurodevelopment: DNA methylation, Prenatal Diet, and Cognitive Stimulation (MEND), ECHO Renewal for the CANOE Study Cohort, Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthma, A South Carolina ECHO Pregnancy Cohort, Childhood Allergy and the NeOnatal Environment in St Louis (CANOE-STL) and the Impact of Wheezing Illnesses on Neurocognitive Development of Preschool Children, Developmental Impact of NICU Exposures (DINE) phase II, Continued follow-up of the Vitamin C and Smoking in Pregnancy (VCSIP) cohorts through the ECHO consortium, focus on Echo-wide protocols, respiratory outcomes, airway function, and epigenetic changes, ECHO-PROTECT Cohort Study Site in Puerto Rico, A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort Study, Prenatal and Early Childhood Pathways To Health: An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory Outcomes, Minnesota HHEAR Targeted Analysis Laboratory, Early Life Stress and the Environmental Origins of Disease: a Population-based Prospective Longitudinal Study of Children in Rural Poverty (ECHO), Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methods, Host genetics, early-life microbiome, and childhood asthma: MARC-43 Boston, Environmental Influences on Child Health Outcomes (ECHO) and Pregnancy in Ohio, Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR), Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory health (LA DREAMERs), Enriching ECHO Cohorts with High-risk Pregnancies and Children with Disabilities (Enriching ECHO), Columbia Center for Children's Environmental Health in ECHO II: Impact of environmental exposures on children's health and the co-morbidity of asthma and ADHD., ECHO in Agricultural Washington and Rural Environments (ECHO AWARE), Developmental Impact of NICU Exposures (DINE), ASSESSING THE EVOLVING IMPACT OF EARLY LIFE EXPOSURES ON CHILD PHYSICAL HEALTH AND NEURODEVELOPMENT, Mount Sinai ECHO site for Perinatal Environment and Development Studies, ECHO Renewal for the INSPIRE Study Cohort, Breaking the cycle of intergenerational disadvantage: neurodevelopment among Puerto Rican children., Prenatal Environment And Child Health (PEACH) in ECHO, Early Life Determinants of Child Health: A New Denver-Based Cohort, The Environmental Factors in FEtal to Childhood Trajectories Cohort, Integrative metabolomic characterization of ADHD and asthma comorbidity, ENVIRONMENTAL INFLUENCES ON NEURODEVELOPMENTAL OUTCOME IN INFANTS BORN VERY PRETERM, Environmental influences on Child Health Outcomes - 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OpenAlex ID: W7124745249